Nicotinic receptor mechanisms and cognition in normal states and neuropsychiatric disorders
نویسندگان
چکیده
منابع مشابه
Nicotinic receptor mechanisms and cognition in normal states and neuropsychiatric disorders.
Cigarette smoking rates in the American population are approximately 23%, whereas rates of smoking in clinical and population studies of individuals with neuropsychiatric disorders are typically two- to four-fold higher. Studies conducted in a variety of neuropsychiatric populations [e.g. attention-deficit hyperactivity disorder (ADHD), Alzheimer's disease, schizophrenia] have collectively sugg...
متن کاملNicotinic Receptor Mechanisms in Neuropsychiatric Disorders: Therapeutic Implications
Nicotinic acetylcholine receptors (nAChRs) are ligandgated ion channels in the central nervous system and consist of α and β subunits. Twelve subtypes of the nAChR have been identified; the α4β2 subunit combination is the most common.1 nAChRs are found in thalamus, basal ganglia, cerebral cortex, hippocampus, and cerebellum.2 Acetylcholine (Ach) is the endogenous ligand of the nAChR. Nicotine i...
متن کاملSpecial Issue: Cognition in Neuropsychiatric Disorders Computational psychiatry
P. Read Montague, Raymond J. Dolan, Karl J. Friston and Peter Dayan 1 Virginia Tech Carilion Research Institute and Department of Physics, Virginia Tech, 2 Riverside Circle, Roanoke, VA 24016, USA 2 Wellcome Trust Centre for Neuroimaging, University College London, 12 Queen Square, London, WC1N 3BG, UK 3 Gatsby Computational Neuroscience Unit, Alexandra House, 17 Queen Square, London, WC1N 3AR, UK
متن کاملCan noninvasive brain stimulation enhance cognition in neuropsychiatric disorders?
Cognitive impairment is a core symptom of many neuropsychiatric diseases and a key contributor to the patient's quality of life. However, an effective therapeutic strategy has yet to be developed. Noninvasive brain stimulation techniques, namely transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), are promising techniques that are under investigation for a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Psychopharmacology
سال: 2004
ISSN: 0269-8811,1461-7285
DOI: 10.1177/026988110401800403